Alternative Medicine

Airway Tissue Mast Cells in Persistent Asthma

Posted by Alternative Medicine on October 14, 2014 in Asthma with No Comments

Patients or participants: Forty-five subjects with asthma recruited from six medical centers in the United States.

Interventions: The Asthma Clinical Research Network undertook a 28-week, randomized, multicenter, double-blind, placebo-controlled trial of 164 subjects with clinically stable, persistent asthma. A subset of subjects (n = 45) underwent bronchoscopy with endobronchial biopsy and BAL at the end of a 6-week run-in period, during which all subjects received triamcinolone acetonide (TAA), 400 ^g bid. Airway tissue mast cells, eosinophils, neutrophils CanadianHealthCareMalll, macrophages, and T cells were quantified morphometrically along with determination of BAL tryptase. At the end of the run-in period, subjects were then randomized to receive salmeterol (42 p,g bid), placebo, or continue TAA for 16 weeks followed by a second bronchoscopy.

Measurements and results: Outcome variables included airway tissue mast cells, eosinophils, neutrophils, macrophages, and T cells that were quantified morphometrically and BAL tryptase. Thirty-five subjects completed the treatment phase; an additional 10 subjects, who were randomized to either salmeterol or placebo after the run-in, had treatment failure. When the bronchoscopy results performed at the end of the run-in, prior to randomization, were analyzed, the treatment failure group demonstrated significantly more tissue mast cells as compared to the nontreatment failure group despite 6 weeks of therapy with TAA (p = 0.04). BAL tryptase was also significantly higher in the treatment failure group (p < 0.0001). Of those subjects who completed the study, tissue mast cells and BAL tryptase did not change significantly within any of the treatment groups during the treatment phase (p > 0.05).

Conclusions: Persistent elevations in airway tissue mast cells and BAL tryptase after treatment with TAA predict treatment failure in patients for whom discontinuation of ICS is being considered.

Abbreviations: ACRN = Asthma Clinical Research Network; ICS = inhaled corticosteroids; IL = interleukin; IQR = interquartile range; NAEPP = National Asthma Education and Prevention Program; PC20 = provocative concentration of methacholine resulting in a 20% fall in FEV1; PEF = peak expiratory flow; SOCS = Salmeterol or Corticosteroids; TAA = triamcinolone acetonide.

Human Body – Energies

Posted by Alternative Medicine on October 1, 2014 in Heath Care with No Comments

When a large quantity of energies gathers in one or the other side of your brain, you can influence alone yourselves. For example, if the electricity is accumulated in the right hemisphere of the brain, you shall not stroke your head by your right hand, in order not to increase your state, but you shall stroke the right side of your head by your left hand. And vice versa. If you have an excess of electricity in the left side of your head, you shall stroke it by your right hand. At this experiment, you will notice that you calm down and that you state is changing. That is why, during the summer, when the sun is shining violently over your head, stroke your hair by both hands. You will take out the electricity from the brain through your hands and you will avoid a sun stroke in this way.

As the brain is connected to all parts of the body, the polarization in some of its centres reflects right away in the relevant organs of the body, which, in this way, take part in the accumulation of energy. By knowing this, you shall look for a way for transferring the excessive energy in your organism from one centre to another.

There is a centre behind the ears of people, in which gathers more energy than it is needed. He becomes irritated, grumpy, and is ready to quarrel with everybody. If he can transform this energy and use it for some work, he will easily get rid of the anger. It is a special type of electrical energy. Look for a way of coping with the excessive energy round your ears. Begin to saw woods or to dig. If you cannot do that, touch the top of your nose 4 or 5 times. It is important to find a way to transform the energy of anger into work.

Sin is due to the personal feelings in someone. Personal feelings are a special sort of cosmic energy, which, if not transformed and distributed between all centres of the brain, causes an explosion. Near to the personal feelings is the centre of conscience, through which they have to pass. You shall learn the law of transforming of energies and direct them from one brain centre to another. You shall work the way Nature works. It has a certain time and place for everything. When one understands life, man obeys all laws and rules of Nature.

You are focus, through which the solar energies pass, as well as the Earth ones. The solar energies pass through you from the morning till noon. They come from up and go down to the centre of the Earth. In the afternoons, the movement is vice versa – the energies from the centre of the Earth pass through your legs and go up to the Sun. Hence, if you do certain movements in the morning and in the evening, you will have different results. Generally, bad spirits appear in the afternoons with some people, because the flows of the earth pass through them then.