Alternative Medicine

How Much You Should Be Spending on Erectile Dysfunction Drugs?

Posted by Alternative Medicine on March 8, 2016 in Erectile Dysfunction with No Comments

Why do people worldwide keep choosing Viagra, Cialis and other drugs for ED cure? The answer is simple: they help to forget about sexual inability and perform regardless of age or health. Why do they turn to Canadian Pharmacy? It’s a unique chance to buy anything a man needs at affordable prices without any need to sacrifice high quality.

Before we share more info about the benefits of turning to Viagra or Cialis at Canadian Pharmacy, let’s find out why people call ED drugs’ cost ever-growing.

Ever-Growing Cost of ED Drugs Makes Men Look for Alternative Choices

Erectile Dysfunction

Popular drugs’ costs always increase rather unexpectedly. Regular Viagra or Cialis users are death on variation of prices and get really frustrated every time there is a new change. It is obvious that the cost of Viagra has grown since 1998:

  • in 1998 Viagra cost $7 per one blue pill;
  • in 2006 – $9.5 per pill;
  • in 2007 – $12 per pill;
  • in 2008-2015 – $19-24 per pill.

Every year the cost keeps rising by 7-9% approximately. But what surprises the most is Cialis: it became twice as expensive over the past 10 years only:

  • in 2003 – $8 per pill;
  • in 2009 – $12-16 per pill;
  • in 2015 – $22 per pill.

As long as this is the case with brand pills, men worldwide keep looking for alternative options and turn to generic pills from Canadian Pharmacy. It is proven that Canadian Cialis and Viagra are as effective, but less harmful. This alternative shopping allows getting the prescribed pills at much lower costs.

What’s the Average Cost of Generic Pills?

When it comes to generic pills, their costs vary from pharmacy to pharmacy. Even Canadian Pharmacy drugs may seem to be pretty expensive for some men, yet they result is worth the money spent:

  • Viagra – $8-12 per pill;
  • Cialis – $5-10 per pill;
  • Levitra – $5-8 per pill;
  • Kamagra – $3-7 per pill.

Can ED Pills Be Covered by Insurance?

Health insurance coverage is what most ED sufferers are seeking. It’s quite easy to understand: the cost of pills keeps growing, while the income remains the same. We will probably disappoint you, but most insurance companies are ambivalent about ED drugs coverage:

  • some insurers pick up the cost;
  • others refuse to cover any part of the ED drug bill.

No state insurance company program will cover the expenses. This is surely a bad news for elderly men, who always need ED medication for a great performance. So, many men turn to private insurance plans that assist in making provisions cover Canadian Viagra as well as most other drugs, if they are prescribed by a doctor.

How to learn whether pills of Canadian Pharmacy are covered by the individual health insurance company? One should examine his insurer’s formulary that always includes the list of medications covered at various rates. A common tendency is such that a formulary has three levels of drugs: Tier I – III. Tier I – medications that involve the cheapest co-pays. They are the most essential, as a rule. Tier II are more expensive or brand-name drugs. In this case a patient pays a greater part of the bill. Tier III drugs are regarded as non-essential, so they’re billed at the highest rate. Guess which drugs are listed as Tier III. It’s Cialis and Viagra, of course.

Is there a chance to make the company pay for ED pills? Yes, there is. Check your formulary and then talk to your doctor about your ED condition and the way it ruins your health and life. After the ED is officially diagnosed, talk to your insurer to determine all existing requirement for covering ED drugs. Then getting pills from Canadian Pharmacy Online will be even easier and cheaper.

Choosing the Best Pharmacy and Comparing Drug Prices

We suggest following a 5-stage route while picking the pharmacy and comparing all prices:

  1. look for drugstores with available generic drugs;
  2. check whether the needed drug is in the insurer’s formulary;
  3. find proofs of store’s safety and legacy;
  4. access the price comparison website;
  5. include the shipping cost.

You get a rare chance to save more, if the generic drug is listed in insurance drug’s formulary. We’ve already mentioned why choose Generic Viagra at Canadian Pharmacy or any other ED pills: they are as effective, yet cheaper.

BUT NOTE: it’s highly important to consult a physician before buying a generic version. What if a cheaper pill is not your cup of tea?

Imagine you have found a store with affordable generic pills that are listed in the formulary. The next step is finding out whether it is legal and safe. There are false pharmacies that do nothing but take clients’ money and provide low-quality drugs or no medications at all. Use one of the price comparison websites that will assist in determining the drugs’ cost. And finally, consider the shipping cost. There are frequent cases when website prices are surprisingly low and the shipping charges make the medication twice as expensive.

How much should you spend on ED? That’s a tricky question, you know. They say one must spend as much as needed for great health issues. We say you should do everything possible to achieve awesome results and forget about ED problems. And if there’s a chance to cut down expenses, then why not use it?

Models of Erectile Dysfunction

Posted by Alternative Medicine on May 26, 2014 in Erectile Dysfunction with No Comments


Hypercholesterolemia and subsequent atheroscle-rosis are well-recognized risk factors for the devel-opment of vasculogenic ED. Viagra online in Australia Rarely is hypercholesterolemia-associated ED in men seen in isolation, without other risk factors such as obesity, smoking, age, and diabetes. Rabbits are the most used species in hypercholesterolemia. A high cholesterol/high triglyceride diet, sometimes com-bined with balloon injury of the aortoiliac arteries, is used to induce atherosclerotic plaques in the arterial supply to the penis. This results in the impairment of endothelium-dependent cavernosal smooth muscle relaxation and agonist-induced penile erection with papaverine. These defects could not be explained solely by the occlusion of blood flow, but were also accompanied by defects in smooth muscle signaling.

Cavernous Nerve Injury

Due to the high prevalence of ED following pelvic surgery as a result of injury to the neurovascular bundle, there has been a great interest in models of cavernous injury. The goal is to identify the mechanisms leading to the ED (e.g., penile apotosis and fibrosis), as well as identifying meth-ods of preventing these pathological changes or remediating them. The most widely used animal model of cavernous nerve injury (CNI) is the cav-ernous nerve-injured rat model. Injury can be induced by crush, cut or freezing rat models. Through a lower abdominal midline incision, the posterolateral area of the prostate is exposed on both sides and the major pelvic ganglions and cavernous nerves are identified. The cavernous nerves, unilaterally or bilaterally, are either sharply divided with knives to remove a segment of nerve, cauterized, or frozen using a thermocouple. ED-observed postradical prostatectomy is most likely attributed to changes in the endothelium and smooth muscle cells from a loss in neural integrity. The absence of neural input to the penis after CNI in the rat results in cavernosal smooth muscle apoptosis, alterations in the endothelium and smooth muscle function, decrease in neuronal NOS nerve fibers in the penis, pelvic ganglia, and fibrosis. The CNI rat model has led to a more thorough understanding of the pathophysiological sequences involved in the development of postradical prostatectomy ED.

Hypogonadism Canadian Health Care mall

Androgens are necessary for the maintenance of the mammalian erectile response. In most animals, androgens are essential in maintaining sexual behavior. However, evidence shows that androgens are also necessary to maintain the erectile apparatus of the penis. Effects of castration on sexual function are evaluated by the observation of copulatory behaviors, penile reflex, and erectile response electrical stimulation of the cavernous nerve. Particularly in the rat model, androgens act centrally to support copulatory behavior and peripherally to maintain constitutive NOS activity and support the veno-occlusive mechanisms. Thus, the erectile response in the rat is androgen dependent. Castrated rats have been used as models to study venoocclusive dysfunction because cavernosal sinusoidal smooth muscle fails to fully relax and blood flow continues during erection in castrated rats, suggesting the failure of venoocclusion. Despite these reports of the importance of androgens in the erectile response of laboratory animals, the role of androgens in the maintenance of the human erectile response remains controversial. Even in severely hypogonadal men, the erectile response is not always lost. Therefore, the hypogonadal animal model of ED may be best utilized as a model of venoocclusive ED.


A large number of models exist for the study of male sexual function. Each model has both strengths and limitations. Care must always be taken before extrapolating too quickly from experimental data to a seemingly parallel clinical situation. Practical considerations have led to a great reliance on rodent models viagra in Canada. These have the advantage of cost, ease of handling, and a large foundation of biological knowledge. There are rodent models for examining every aspect of penile erection from higher neural control down to molecular events within the erectile tissue. The disadvantage of rodent models is that they do not always accurately reflect human physiology and pathophysiology, although they seem to share many basic mechanisms. Therefore, the validation of any given model must be assessed for a particular application. The utility of these models is amply demonstrated by the great expansion of our understanding of male sexual physiology in recent years. Future challenges will be to develop more models of pathophysiological conditions.